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Average PA-824 plasma concentration-versus-time curves (log scale) after administration of PA-824 as the following treatments and at the indicated doses: i.v. solution (IV) at 20 mg/kg; oral mixed micelle suspension (Oral) at 40 mg/kg; and insufflated (Insuff) PA-824 dry powder porous particles at 20, 40, and 60 mg/kg. Values are mean ± standard deviations (n = 6 or 7).
