FIG. 6.

Effect of IL-1R1 and TNF-αR1/2 on neutrophil and eosinophil recruitment to the corneal stroma. C57BL/6, TNF-αR1/2^−/−, and IL-1R1^−/− mice were immunized with OvAg subcutaneously and then injected into the corneal stroma with OvAg. The number of neutrophils and eosinophils per 5-μm section was determined by immunohistochemistry. The data are means ± the SEM with five mice per group and are representative of three repeat experiments. Note the decreased neutrophil numbers in IL-1R1^−/− mice compared to C57BL/6 mice.