FIG. 3.

CXCL10 inhibits B. anthracis spore germination prior to cortex degradation. B. anthracis 7702 spores with or without 48 μg/ml CXCL10 were visualized 6 h posttreatment using TEM. Whereas untreated spores underwent germination and were visualized as vegetative bacilli, CXCL10-treated spores failed to germinate and closely resembled spores taken from the initial inoculum. Representative fields from two independent experiments are shown at a ×30,000 magnification; the scale bar equals 0.5 μm.