TABLE 3.

Cecum and colon inflammation scores of mice persistently infected with different B. fragilis strains^a

Strain or type of infection	Median (range) inflammation score, no. of mice at:
	1 mo		3 mo		8 mo		16 mo
	Cecum	Colon	Cecum	Colon	Cecum	Colon	Cecum	Colon
Mock	0.0 (0-1), 6	0.0 (0-0.5), 3	ND	ND	0.0 (0), 3	0.0 (0), 3	0.0 (0-1), 4	0.0 (0), 4
WT-ETBF (bft-2)	2.25 (2-3), 8*	1.0 (0.5-1.5), 5*	2.0 (2-3), 5*	2.0 (1-2), 5*	2.0 (1-2), 3*	1.0 (0-1), 3	2.5 (2-3), 6*	2.5 (2-3), 6*
WT-NTBF	0.0 (0-1), 7	0.0 (0), 4	0.5 (0-1), 4	0.0 (0), 4	0.0 (0), 3	0.0 (0), 3	0.0 (0-1), 8	0.0 (0-1), 8
rETBF (bft-2)	3.0 (3), 3**	ND	ND	ND	ND	ND	1.0 (1-3), 9**	1.0 (0-3), 9**
rNTBF (bft-2 H352Y)	0.0 (0-1), 3	ND	ND	ND	ND	ND	ND	ND

^aThe Mann-Whitney U test was used to compare between-group distributions for unpaired data. *, a P value of <0.05 compared with mock-infected and WT-NTBF-infected mice; **, a P value of <0.05 compared with rNTBF- and WT-NTBF-infected mice. ND, not determined.