FIG. 2.

Susceptible BALB/c mice survive T. cruzi infection produced by an intranasal inoculum that would otherwise be lethal if they are injected subcutaneously. Parasitemia (A), survival (B), and brain parasite loads (C) of BALB/c mice inoculated with 0.5 × 10³ T. cruzi trypomastigotes intranasally (i.n.) or subcutaneously (s.c.). Brain parasite loads of resistant C57BL/6 mice 25 days after subcutaneous or intranasal inoculation with the same number of parasites are shown in panel C for comparison with BALB/c mice. *, P < 0.05. Experiments were repeated three times, using two to four mice/time point.