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Scheme for the interaction between myosin, actin, and ATP. The partners are depicted as spheres whose separation is kept constant by the spacer SP. Free binding energy is transferred by shifting of the myosin plunger PL that interacts with actin and ATP. With a stiff plunger (a) a high activation energy is to be expected. With an elastic plunger (b–d) an activation energy can be avoided.
