FIG. 2.

EbolaΔVP30 virus induces an antibody response to the EBOV glycoprotein GP. Mice (n = 4) were vaccinated with EbolaΔVP30 virus three times at 3-week intervals, whereas nonvaccinated mice (n = 4) were inoculated with PBS. Serum samples were collected 2 weeks after each vaccination, and the amounts of IgG against purified EBOV GP were determined by ELISA, as described in Materials and Methods. Results are expressed as the mean absorbance (optical density [OD]) at 405 nm (± standard deviation) of samples diluted to 1:100.