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Mutations capable of converting the multiple HBeAg forms of genotype A into a single-size form. (A) Amino acid sequences of three site-directed mutants of clone A2 and one mutant of clone B2. The triangle size indicates the efficiency of cleavage in Huh7 cells. (B and C) HBeAg expression from Huh7 and HepG2 cells, respectively. Numbers shown to the right indicate the motifs recognized. Mock, mock transfected.
