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. 2009 Feb 4;83(8):3450–3462. doi: 10.1128/JVI.02561-08

FIG. 4.

FIG. 4.

Effect of transgene insertion on virus growth and cytotoxicity of armed MAV-1 vectors. 3T6 murine fibroblasts (A) and Pan02 murine tumor cells (B) were infected with dlE102, DLFM, or DMFL at an MOI of 5 PFU/cell in duplicate, and the supernatants were collected at 24, 48, and 72 h postinfection. Viral yield was determined by a TCID50 assay, and the data were plotted as the TCID50 (PFU per milliliter) versus time. (C) EC50s were generated on both 3T6 and Pan02 cells as described in the legend to Fig. 1.