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Immunofluorescence labeling in the olfactory nerve of a scrapie-affected sheep. (A to C) Double immunofluorescence for PrPSc and carnosine (magnification, ×60). (A) Anti-PrP (Cy3, red); (B) anticarnosine (Cy2, green); (C) overlay of panels A and B. (D to F) Immunofluorescence for PrPSc and cytokeratins (magnification, ×60). (D) Anti-PrP (Cy3, red); (E) anticytokeratins (Cy2, green); (F) overlay of panels D and E.
