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. 2009 Feb 17;29(8):2322–2334. doi: 10.1128/MCB.01543-08

FIG. 7.

FIG. 7.

The DN forms of Beta2/NeuroD1 and Maf inhibit transcription from the PC2 promoter. (a) InR1G9 cells were transiently transfected with the −633-bp PC2 promoter together with the cDNA that codes for DN-Beta2/NeuroD1 (DN-Beta2) or DN-Maf. Results represent relative CAT and Luc activities over the basal levels for each construct. (b) InR1G9 cells were transiently transfected with the −1,228-bp 7B2 promoter together with the cDNA that codes for DN-Beta2/NeuroD1, DN-Maf, or DN-Pax6. Results represent relative Luc and PAP activities over the basal levels for each construct. (c) InR1G9 cells were transiently transfected with the Enhancer-CMV-Basic reporter used as a control, together with increasing concentrations of the cDNA encoding the DN form of the transcription factor. Results represent relative CAT and Luc activities over the basal levels for each construct. The total DNA transfected was kept constant at 3 μg. Values are the means ± the standard errors of the means from at least three separate experiments, each performed twice. **, P < 0.01 (compared with the control).