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. 2009 Feb 17;29(8):2322–2334. doi: 10.1128/MCB.01543-08

FIG. 8.

FIG. 8.

Overexpression of cMaf or Beta2/NeuroD1+E47 can rescue the decreased PC2 and 7B2 promoter activities in Pax6-DN306 clones. PC2 and 7B2 promoter activities in Pax6-DN306 clones overexpressing cMaf and Beta2/NeuroD1. The A5 and C4 clones were transfected with either the −633-bp PC2 human promoter linked to the CAT reporter or the empty reporter vector (pCAT-Basic) (a) or to the −1,228-bp mouse 7B2 promoter or the empty reporter (pGL2-Basic) (b) together with the annotated transcription factors. Results represent relative CAT and Luc or Luc and PAP activities over the basal levels for each construct. Values are the means ± the standard errors of the means from at least three separate experiments, each performed twice. *, P < 0.05 (compared with the control).