Fig. 2.
Effect of phenylephrine on GABAergic sIPSCs in lamina II neurons before and after WB4101 application. A, original traces of sIPSCs during control and application of 50 μM phenylephrine with and without 0.5 μM WB4101 in one lamina II neuron. B, cumulative probability plots of the same neuron in A show the distribution of inter-event interval and amplitude of sIPSCs during control and application of phenylephrine and phenylephrine plus WB4101. C, summary data show that 0.5 μM WB4101 abolished the effect of 50 μM phenylephrine on the frequency of sIPSCs (n = 9). D, group data show the reproducible effect of 50 μM phenylephrine on the frequency of sIPSCs (n = 8). Data presented as means ± S.E.M. *, P < 0.05 compared with the baseline control. Phl, phenylephrine; WB, WB4101.