Table 3.

Total body BCM and BMD z-scores versus the presence or absence of skeletal fractures, scoliosis, seizures, anticonvulsant use, and ambulatory status in girls and women (n = 50) with Rett syndrome

Variable	Number of subjects	BMC z-score*	BMD z-score*
Presence of seizures
Yes	32	-2.4 ± 1.0**	-2.0 ± 1.1
No	17	-1.8 ± 0.9	-1.3 ± 1.2
Ever used anticonvulsants
Yes	34	-2.4 ± 0.9†	-2.1 ± 1.0†
No	15	-1.5 ± 0.9	-1.0 ± 1.3
Currently using anticonvulsants
Yes	25	-2.2 ± 1.2	-1.8 ± 1.3
No	24	-2.1 ± 0.8	-1.6 ± 1.1
Presence of scoliosis
Yes	31	-2.4 ± 1.0	-2.0 ± 1.1**
No	18	-1.8 ± 1.0	-1.3 ± 1.3
Ever walked
Yes	42	-2.2 ± 1.0	-1.9 ± 1.0
No	7	-1.9 ± 1.2	-0.6 ± 1.5
Currently walks without assistance
Yes	37	-2.2 ± 0.9	-1.9 ± 1.0
No	12	-2.2 ± 1.3	-1.2 ± 1.7
Occurrence of skeletal fractures
Yes	13	-3.0 ± 0.9‡	-2.6 ± 1.0†
No	36	-1.8 ± 0.9	-1.4 ± 1.1

^*Values expressed as mean ± SD

^**P<0.05

^†P<0.01

^‡P<0.001