TABLE 3.

Proposed adult dosing guidelines for colistin (as base equivalent)

Creatinine clearance	>90 mL/min	60–90 mL/min	30–60 mL/min	<30 mL/min
Divided doses	100 mg IV q8h (up to 100–125 mg IV q6h)	75–100 mg IV q12h	75–150 mg daily or q12h	100–150 mg IV q36h
Total daily	5 mg/kg/day	2.5–3.8 mg/kg/day	2.5 mg/kg/day	1.5 mg/kg/day

IV Intravenous; q Every