TABLE 2.
Calculated cut-off, sensitivity, specificity, and AUC values for ANP, BNP, cTnI and CRP levels, and APACHE II scores at discharge/death outcome (last day)
| Cut-off | Sensitivity (%) | Specificity (%) | AUC | P | ||
|---|---|---|---|---|---|---|
| Day 1 | ANP | >47.6 | 70 | 90 | 0.819 | 0.001 |
| BNP | >32.1 | 100 | 95 | 0.990 | <0.001 | |
| cTnI | ≤0.03 | 50 | 65 | 0.425 | 0.417 | |
| CRP | >7.1 | 75 | 55 | 0.551 | 0.579 | |
| APACHE II | >23 | 45 | 90 | 0.731 | 0.012 | |
| Day 2 | ANP | >15.4 | 90 | 95 | 0.955 | <0.001 |
| BNP | >23.9 | 100 | 100 | 1.000 | <0.001 | |
| cTnI | >0.03 | 65 | 85 | 0.764 | 0.004 | |
| CRP | >5.6 | 80 | 65 | 0.774 | 0.003 | |
| APACHE II | >20 | 90 | 85 | 0.943 | <0.001 | |
| Last day | ANP | >9.8 | 100 | 95 | 0.998 | <0.001 |
| BNP | >20.1 | 100 | 100 | 1.000 | <0.001 | |
| cTnI | >0.03 | 85 | 95 | 0.948 | <0.001 | |
| CRP | >6.6 | 85 | 95 | 0.958 | <0.001 | |
| APACHE II | >17 | 100 | 100 | 1.000 | <0.001 | |
APACHE II Acute Physiology and Chronic Health Evaluation; AUC Area under the curve; ANP Atrial natriuretic peptides, pg/mL; BNP Brain natriuretic peptides, pg/mL; CRP C-reactive protein, mg/L; cTnI Cardiac troponin I, μg/L