Table 4.
Body composition characteristics associated with major weight gain
| Characteristic | Major weight gain | Treatment group | n | First quartile | Median | Third quartile | Adjusted mean* | P value for treatment group† | P value for weight gain‡ |
|---|---|---|---|---|---|---|---|---|---|
| Percent body fat | |||||||||
| Men | Yes | INT | 38 | 24.5 | 27.1 | 31.7 | 25.9 | <0.0001 | |
| CON | 5 | 23.0 | 24.7 | 28.7 | 24.3 | 0.3733 | |||
| No | INT | 260 | 15.1 | 19.2 | 22.7 | 17.8 | 0.1479 | ||
| CON | 332 | 14.7 | 18.4 | 23.2 | 17.2 | 0.0076 | |||
| Women§ | Yes | INT | 67 | 36.8 | 38.9 | 41.6 | 39.8 | <0.0001 | |
| CON | 9 | 36.3 | 38.1 | 40.8 | 40.1 | 0.5958 | |||
| No | INT | 220 | 27.0 | 30.7 | 34.0 | 32.3 | 0.2342 | ||
| CON | 249 | 26.8 | 30.3 | 33.9 | 31.9 | <0.0001 | |||
| Fat-free mass (kg) | |||||||||
| Men | Yes | INT | 38 | 65.8 | 69.4 | 78.5 | 68.8 | <0.0001 | |
| CON | 5 | 67.6 | 67.9 | 73.7 | 66.9 | 0.7189 | |||
| No | INT | 260 | 60.4 | 65.3 | 70.6 | 63.2 | <0.0001 | ||
| CON | 332 | 60.3 | 64.8 | 70.9 | 61.6 | 0.0131 | |||
| Women | Yes | INT | 67 | 47.8 | 53.3 | 56.5 | 54.9 | <0.0001 | |
| CON | 9 | 47.4 | 50.9 | 54.8 | 53.8 | 0.2537 | |||
| No | INT | 220 | 43.1 | 45.7 | 49.5 | 51.0 | 0.0019 | ||
| CON | 249 | 42.4 | 45.3 | 48.7 | 50.1 | 0.0005 |
*
Least-squares estimates of cell means after adjusting for covariance with weight at baseline
†
from the Wilcoxon’s test of differences between treatment groups within weight-gain categories after adjusting for covariance with weight at baseline
‡
from the Wilcoxon’s test of differences between patients with and without major weight gain within treatment groups after adjusting for covariance with weight at baseline
§
includes all women randomized as adults. Excluding women who became pregnant during the trial yields substantially identical results. INT, intensive; CON, conventional.