Skip to main content
. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: Immunogenetics. 2008 Sep 17;60(12):711–725. doi: 10.1007/s00251-008-0331-1

Linkage Disequilibrium Analysis of KIR Genes in CEPH

2DS2 2DL2 2DL3 2DL5B 2DP1 2DL1 3DL1 3DS1 2DL5A 2DS3 2DS5 2DS1 2DS4

2DS2 AFR 0.96 -0.36 0.33 -0.16 -0.17 -0.13 0.09 -0.13 0.45 0.26 0.18 -0.16
EUR 0.99 -0.29 0.66 -0.17 -0.17 -0.02 0.16 -0.33 0.56 0.08 0.14 -0.02
SWA 0.95 -0.28 0.67 -0.14 -0.14 -0.14 0.19 -0.30 0.52 0.18 0.18 -0.15
EAS 0.99 -0.40 0.38 -0.31 -0.31 -0.06 0.23 -0.27 0.30 0.20 0.18 -0.06
OCE 0.85 -0.23 0.20 -0.15 -0.15 -0.07 0.04 -0.21 0.25 0.06 0.07 -0.07
NEA 0.80 -0.38 0.72 -0.05 -0.18 -0.05 0.21 -0.39 0.58 0.26 0.31 -0.05
NAM 1.00 -0.30 0.42 -0.30 -0.30 -0.34 0.12 -0.29 0.18 0.25 0.25 -0.34
SAM 1.00 -0.29 0.85 -0.29 -0.29 -0.26 0.11 -0.68 0.03 0.38 0.44 -0.26

2DL2 AFR 6/6 -0.38 0.45 -0.16 -0.17 -0.12 0.07 -0.24 0.46 0.30 0.15 -0.15
EUR 7/7 -0.30 0.67 -0.17 -0.17 -0.01 0.15 -0.34 0.55 0.07 0.13 0.00
SWA 2/2 -0.29 0.77 -0.14 -0.14 -0.14 0.18 -0.33 0.44 0.22 0.22 -0.15
EAS 6/6 -0.39 0.52 -0.30 -0.30 -0.06 0.23 -0.50 0.30 0.22 0.19 -0.06
OCE 1/2 -0.19 0.22 -0.13 -0.13 -0.19 0.07 -0.17 0.26 0.20 0.09 -0.19
NEA 1/1 -0.31 0.33 -0.10 -0.23 -0.10 0.19 -0.09 0.21 0.25 0.32 -0.10
NAM 2/2 -0.30 0.42 -0.30 -0.30 -0.34 0.12 -0.29 0.18 0.25 0.25 -0.34
SAM 3/3 -0.29 0.85 -0.29 -0.29 -0.26 0.11 -0.68 0.03 0.38 0.44 -0.26

2DL3 AFR 4/6 4/6 -0.21 0.39 0.36 0.18 -0.12 0.10 -0.31 -0.17 -0.15 0.16
EUR 4/7 4/7 -0.25 0.55 0.55 0.11 -0.13 0.16 -0.29 -0.13 -0.13 0.10
SWA 1/2 1/2 -0.04 0.53 0.53 0.17 -0.07 0.02 -0.24 -0.03 -0.01 0.17
EAS 1/4 1/4 -0.45 0.68 0.68 -0.05 -0.04 0.45 -0.25 -0.05 -0.01 -0.05
OCE 0/2 0/2 -0.30 0.69 0.69 0.62 -0.03 -0.06 -0.03 -0.11 -0.04 0.62
NEA 1/1 0/1 -0.53 0.32 0.48 -0.06 0.10 0.70 -0.38 -0.18 -0.17 -0.06
NAM 2/2 2/2 -0.17 1.00 1.00 0.30 -0.11 0.11 0.04 -0.20 -0.17 0.30
SAM 2/3 2/3 -0.24 1.00 1.00 0.34 -0.04 0.28 0.08 -0.11 -0.15 0.34

2DL5B AFR 1/4 1/4 0/4 -0.06 -0.10 -0.06 -0.64 -0.68 0.36 -0.30 -0.53 -0.11
EUR 7/7 7/7 2/6 0.09 0.09 0.04 -0.40 -0.45 0.79 -0.44 -0.39 0.05
SWA 2/2 2/2 1/2 - - -0.19 -0.22 -0.44 0.56 0.03 0.06 -0.19
EAS 1/5 1/4 0/3 0.33 0.33 0.12 -0.65 -0.81 0.46 -0.22 -0.72 0.12
OCE 0/2 0/2 0/1 -0.11 -0.11 -0.30 -0.32 -0.32 0.61 -0.05 0.03 -0.30
NEA 1/1 0/1 1/1 -0.25 -0.25 -0.06 -0.53 -0.53 0.83 -0.45 -0.36 -0.06
NAM 2/2 2/2 0/2 -0.17 -0.17 -0.28 -0.57 -0.68 0.37 -0.37 -0.12 -0.28
SAM 2/2 2/2 0/2 -0.24 -0.24 -0.08 -0.79 -0.83 0.19 - - -0.08

2DP1 AFR 0/4 0/4 2/4 0/1 0.95 0.32 0.08 0.09 0.15 0.14 0.03 0.16
EUR 0/5 0/5 4/5 0/5 1.00 -0.03 -0.04 0.06 0.10 -0.16 -0.10 -0.03
SWA 0/2 0/2 2/2 0/0 1.00 -0.03 0.07 - 0.14 0.10 0.11 -0.03
EAS 0/3 0/3 2/3 0/1 1.00 -0.05 0.04 -0.15 0.14 0.02 0.04 -0.05
OCE 0/2 0/2 1/2 0/1 1.00 0.53 0.17 0.16 0.03 -0.16 0.04 0.53
NEA 0/1 0/1 0/1 0/1 0.70 -0.04 0.17 0.47 0.11 -0.02 -0.02 -0.04
NAM 2/2 2/2 2/2 0/2 1.00 0.30 -0.11 0.11 0.04 -0.20 -0.16 0.30
SAM 2/3 2/3 3/3 0/2 1.00 0.34 -0.04 0.28 0.08 -0.11 -0.15 0.34

2DL1 AFR 0/4 0/4 2/4 0/2 4/4 0.32 0.09 0.13 0.17 0.09 0.04 0.15
EUR 0/5 0/5 4/5 0/5 5/5 -0.03 -0.03 0.06 0.10 -0.16 -0.10 -0.03
SWA 0/2 0/2 2/2 0/0 2/2 -0.03 0.07 - 0.14 0.10 0.11 -0.03
EAS 0/3 0/3 2/3 0/1 3/3 -0.05 0.04 -0.15 0.14 0.02 0.04 -0.05
OCE 0/2 0/2 1/2 0/1 2/2 0.53 0.17 0.16 0.03 -0.16 0.04 0.53
NEA 0/1 0/1 0/1 0/1 1/1 -0.03 0.12 0.47 0.07 -0.16 -0.15 -0.03
NAM 2/2 2/2 2/2 0/2 2/2 0.30 -0.11 0.11 0.04 -0.20 -0.16 0.30
SAM 2/3 2/3 3/3 0/2 3/3 0.34 -0.04 0.28 0.08 -0.11 -0.15 0.34

3DL1 AFR 0/3 0/3 0/3 0/1 0/2 0/2 -0.20 0.09 0.10 -0.20 -0.29 0.85
EUR 0/7 0/7 0/7 1/7 0/5 0/5 -0.27 -0.21 -0.18 -0.30 -0.25 1.00
SWA 0/2 0/2 1/2 0/2 0/2 0/2 -0.25 -0.18 -0.23 -0.25 -0.29 1.00
EAS 0/5 0/5 0/3 0/4 0/2 0/2 -0.20 -0.09 -0.26 -0.24 -0.21 1.00
OCE 0/2 0/2 1/2 0/1 1/2 1/2 -0.23 -0.28 -0.03 -0.21 -0.04 1.00
NEA 0/1 0/1 0/1 0/1 0/1 0/1 -0.24 -0.13 -0.14 -0.23 -0.22 1.00
NAM 2/2 2/2 1/2 0/2 1/2 1/2 -0.20 0.06 0.04 -0.25 -0.25 1.00
SAM 2/3 2/3 1/3 0/2 1/3 1/3 -0.27 -0.20 -0.07 -0.26 -0.25 1.00

3DS1 AFR 0/6 0/6 1/6 2/4 0/4 0/4 0/3 0.95 0.16 0.39 0.68 -0.18
EUR 1/7 1/7 1/7 6/7 0/5 0/5 3/7 0.94 0.30 0.82 0.92 -0.27
SWA 0/2 0/2 0/2 1/2 0/2 0/2 1/2 0.70 0.46 0.70 0.76 -0.27
EAS 1/6 1/6 0/4 0/4 0/3 0/3 0/5 0.80 0.55 0.80 0.94 -0.20
OCE 0/2 0/2 0/2 0/2 0/2 0/2 0/2 1.00 0.09 0.49 0.52 -0.23
NEA 0/1 0/1 0/1 1/1 0/1 0/1 0/1 1.00 0.28 0.88 0.92 -0.24
NAM 0/2 0/2 0/2 2/2 0/2 0/2 1/2 0.85 0.13 0.83 0.88 -0.20
SAM 1/3 1/3 0/3 2/2 0/3 0/3 1/3 0.95 0.19 0.82 0.78 -0.27

2DL5A AFR 0/5 1/5 0/5 3/4 0/1 0/2 0/1 5/5 -0.07 0.30 0.72 0.16
EUR 2/7 2/7 0/6 6/7 0/5 0/5 1/7 6/7 -0.30 0.72 0.92 -0.21
SWA 1/2 1/2 0/2 1/2 0/0 0/0 1/2 1/2 -0.11 0.39 0.45 -0.20
EAS 1/4 1/3 0/3 2/4 0/1 0/1 0/3 1/4 -0.26 0.48 0.94 -0.09
OCE 0/2 0/2 0/2 0/2 0/2 0/2 0/2 2/2 -0.09 0.37 0.47 -0.28
NEA 0/1 0/1 1/1 1/1 0/1 0/1 0/1 1/1 -0.31 0.51 0.68 -0.13
NAM 0/2 0/2 0/2 2/2 0/2 0/2 0/2 2/2 0.06 -0.06 0.21 0.06
SAM 2/2 2/2 0/2 2/2 0/2 0/2 0/2 2/2 0.19 - - -0.20

2DS3 AFR 4/6 4/6 1/6 0/4 0/4 0/4 0/3 0/6 0/5 -0.14 0.12 0.13
EUR 7/7 7/7 4/7 5/7 0/5 0/5 1/7 3/7 4/7 0.11 0.27 -0.17
SWA 2/2 2/2 1/2 2/2 0/2 0/2 0/2 2/2 1/2 0.24 0.28 -0.24
EAS 3/6 3/6 1/4 1/5 0/3 0/3 0/5 7/7 0/4 0.08 0.47 -0.26
OCE 1/2 1/2 0/2 0/2 0/2 0/2 0/2 0/2 0/2 -0.15 0.17 -0.03
NEA 1/1 0/1 1/1 1/1 0/1 0/1 0/1 0/1 0/1 0.26 0.34 -0.14
NAM 0/1 0/1 0/1 0/1 0/1 0/1 0/1 0/1 0/1 -0.17 0.11 0.04
SAM 0/2 0/2 0/2 0/1 0/2 0/2 0/2 0/2 0/1 0.16 0.16 -0.07

2DS5 AFR 1/6 2/6 1/6 0/4 0/4 0/4 0/3 3/6 1/5 0/6 0.49 -0.23
EUR 0/7 0/7 0/7 4/7 1/5 1/5 3/7 7/7 6/7 2/7 0.84 -0.30
SWA 0/2 1/2 1/2 0/2 0/2 0/2 1/2 2/2 1/2 1/2 0.93 -0.28
EAS 1/6 1/6 0/4 1/5 0/3 0/3 0/5 6/6 2/4 1/6 0.84 -0.24
OCE 0/2 0/2 0/2 0/2 0/2 0/2 0/2 1/2 0/2 0/2 0.46 -0.21
NEA 0/1 0/1 0/1 0/1 0/1 0/1 0/1 1/1 0/1 0/1 0.96 -0.23
NAM 1/2 1/2 0/2 0/1 0/2 0/2 1/2 2/2 0/1 0/1 0.95 -0.25
SAM 2/3 2/3 0/3 0/0 0/3 0/3 1/3 3/3 0/0 0/2 0.96 -0.26

2DS1 AFR 1/6 1/6 1/6 1/4 0/4 0/4 0/3 4/6 3/4 0/6 4/6 -0.28
EUR 0/7 0/7 0/7 6/7 0/5 0/5 2/7 7/7 6/7 2/7 7/7 -0.25
SWA 0/2 1/2 0/2 0/2 0/2 0/2 1/2 2/2 1/2 1/2 2/2 -0.31
EAS 1/6 1/6 0/4 2/3 0/3 0/3 0/5 7/7 3/3 4/7 6/6 -0.21
OCE 0/2 0/2 0/2 0/2 0/2 0/2 0/2 1/2 1/2 1/2 1/2 -0.04
NEA 1/1 1/1 0/1 0/1 0/1 0/1 0/1 1/1 1/1 1/1 1/1 -0.22
NAM 1/2 1/2 0/2 0/1 0/2 0/2 1/2 2/2 0/1 0/1 2/2 -0.25
SAM 3/3 3/3 0/3 0/0 0/3 0/3 1/3 3/3 0/0 0/2 3/3 -0.25

2DS4 AFR 0/3 0/3 0/3 0/1 0/2 0/2 2/3 0/3 0/1 0/3 0/3 0/3
EUR 0/7 0/7 0/7 1/7 0/5 0/5 7/7 3/7 1/7 1/7 3/7 2/7
SWA 0/2 0/2 1/2 0/2 0/2 0/2 2/2 1/2 1/2 0/2 1/2 1/2
EAS 0/5 0/5 0/3 0/4 0/2 0/2 5/5 0/5 0/3 0/5 0/5 0/5
OCE 0/2 0/2 1/2 0/1 1/2 1/2 2/2 0/2 0/2 0/2 0/2 0/2
NEA 0/1 0/1 0/1 0/1 0/1 0/1 1/1 0/1 0/1 0/1 0/1 0/1
NAM 2/2 2/2 1/2 0/2 1/2 1/2 2/2 1/2 0/2 0/1 1/2 1/2
SAM 2/3 2/3 1/3 0/2 1/3 1/3 3/3 1/3 0/2 0/2 1/3 1/3