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K-ras gene status and response to therapy
| Group | K12-ras gene mutation/total (%) |
Positive therapy response (%) | P Value |
|
| Mutant | Wild type | |||
| Controls | 0/75 (0) | __ | __ | __ |
| MGUS | 1/66 (1.5) | __ | __ | __ |
| MM | 20/73 (27.4) | 26.9 | 58.3 | 0.01 |
Statistical significance for K12-ras gene mutation: Control vs MGUS p = 0.95, Control vs MM p = 0.0001, MGUS vs MM p < 0.0001, Positive therapy response: minor response and no change disease (see Methods).
