Table 3.

Onset-to-Treatment and Arrival-to-Treatment Times in Patients Who Received Standard of Care tPA Compared With Patients Participating in Clinical Studies That Either Required Prelytic or Postlytic Enrollment

Variable	Not Enrolled	Studies With Postlytic Enrollment	Studies With Prelytic Enrollment	P Value
	(N=225)	46/65 (70.8%)	19/65 (29.2%)
Onset-to-arrival, median (range)	66 (17–137)	60 (25–120)	59 (15–116)	NS
Onset-to-treatment, median (range)	135 (64–180)	126 (64–180)	128 (92–178)	NS
Arrival-to-treatment, median (range)	62 (20–131)	59 (23–135)	72 (52–111)	0.027*
				0.56†
				0.028‡

^*Comparison of nonenrolled patients with patients that were enrolled in prelytic studies.

^†Comparison of nonenrolled patients with patients that were enrolled in postlytic studies.

^‡Comparison of patients enrolled in pre- versus postlytic studies.

NS indicates nonsignificant.