Table III.
Drug Loading, Particle Size, Release Efficiency up to 8 h of Release Test (RE8%), and MRT of Chitosan Beads Loaded with Gliclazide (n = 3)
| Formulation code | Mean particle size (mm) | Drug loading (%) | RE8 (%) | MRT (h) |
|---|---|---|---|---|
| CL1T2P2t10 | 1.1 ± 0.05 | 41.8 ± 0.57 | 75.03 ± 0.05 | 1.73 ± 0.01 |
| CM2T2P2t20 | 1.45 ± 0.04 | 24.86 ± 0.45 | 53.30 ± 1.52 | 3.60 ± 0.09 |
| CL2T5P2t20 | 1.30 ± 0.04 | 19.0 ± 0.25 | 59.00 ± 2.50 | 3.21 ± 0.15 |
| CM1T5P2t10 | 1.22 ± 0.05 | 38.0 ± 0.52 | 67.93 ± 0.90 | 1.83 ± 0.04 |
| CL1T2P9.6t20 | 1.19 ± 0.02 | 34.6 ± 0.66 | 64.00 ± 2.60 | 2.26 ± 0.07 |
| CM2T2P9.6t10 | 1.58 ± 0.03 | 20.0 ± 1.02 | 43.00 ± 2.00 | 3.22 ± 0.05 |
| CL2T5P9.6t10 | 1.38 ± 0.04 | 23.8 ± 1.00 | 46.30 ± 0.55 | 2.31 ± 0.12 |
| CM1T5P9.6t20 | 1.28 ± 0.03 | 33.0 ± 1.12 | 66.50 ± 0.75 | 2.65 ± 0.05 |