Table I.

In Vitro Permeation of CDL from Different Formulations Across Excised Rat Epidermis

Treatment	Flux (μg/cm2/hr)	Enhancement Ratio (ER)
Donor Formulation PG/ETOH (7:3)	22.79 ± 2.34	–
Buffer (pH 6)	20.6 ± 1.81	–
AR (0.5% w/v)	34.78 ± 3.08	1.53
AR (1% w/v)	121.61 ± 5.39	5.34
AR (2.5% w/v)	98.36 ± 4.62	4.32
AR (5% w/v)	70.59 ± 3.88	3.09
AR (10% w/v)	62.39 ± 4.15	2.74
CTN (1% w/v)	103.5 ± 5.19	4.54
CTN (1% w/v) + AR (1% w/v)	157.69 ± 8.46	6.92

PG propylene glycol, ETOH ethanol, CTN chitosan, AR A. racemosus extract dissolved in PG/ETOH mixture