Table II.
In Vitro Permeation of CDL Across Epidermis Excised after Treatment of Viable Rat Epidermis
Formulation | Excision time (h) | Flux (μg/cm2/h) | Enhancement ratio (ER) |
---|---|---|---|
AR | 4 | 25.17 ± 1.88 | 1.10 |
12 | 80.75 ± 4.94 | 3.54 | |
24 | 65.59 ± 4.02 | 2.88 | |
48 | 44.41 ± 2.46 | 1.95 | |
CTN | 4 | 24.94 ± 1.05 | 1.09 |
12 | 60.13 ± 3.68 | 2.64 | |
24 | 33.28 ± 2.82 | 1.46 | |
48 | 30.29 ± 2.91 | 1.33 | |
AR + CTN | 4 | 79.69 ± 4.35 | 3.36 |
12 | 91.65 ± 5.08 | 4.02 | |
24 | 64.51 ± 3.98 | 2.83 | |
48 | 50.90 ± 2.88 | 2.23 |