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. 2009 Feb 24;10(1):199. doi: 10.1208/s12249-009-9198-1

Table III.

Effect of Treatment with A. racemosus Extract, Chitosan, or Their Mixture on Microconstituents of Epidermis in Excised and Viable Rat Skin

Formulation Skin microconstituent extracted (%)
Cholesterol Triglyceride Sphingosine
Skin type: excised
 AR (0.5%) 18.198 ± 2.01 6.59 ± 0.59 5.863 ± 0.851
 AR (1%) 22.05 ± 2.65 16.54 ± 2.06 13.578 ± 1.87
 AR (2.5%) 38.58 ± 3.94 21.681 ± 3.99 19.962 ± 2.06
 AR (5%) 43.585 ± 4.68 36.6 ± 4.28 25.731 ± 2.64
 AR (10%) 57.732 ± 6.13 38.35 ± 3.64 29.457 ± 3.58
 CTN (1%) 19.120 ± 2.17 6.019 ± 0.58 7.346 ± 0.58
 CTN (1%) + AR (1%) 69.251 ± 4.35 49.11 ± 2.16 35.99 ± 1.97
Skin type: viable
 CTN (1% w/v)
4 h 1.711 ± 0.98 1.91 ± 0.25 0.6872 ± 0.27
 12 h 7.105 ± 1.108 12.001 ± 2.01 2.4023 ± 0.077
 24 h 2.526 ± 0.99 0.501 ± 0.11 0.28685 ± 0.061
 48 h 2.011 ± 0.839 0.489 ± 0.884 0.2015 ± 0.624
 AR (1% w/v)
 4 h 10.831 ± 0.91 8.993 ± 0.73 6.5016 ± 0.21
 12 h 21.33 ± 2.34 14.974 ± 1.68 11.25 ± 1.32
 24 h 12.33 ± 1.432 5.392 ± 0.66 5.61 ± 0.68
 48 h 6.665 ± 1.24 2.186 ± 0.69 1.008 ± 0.57
 AR (1%) + CTN (1%)
 4 h 14.263 ± 0.69 12.314 ± 0.68 8.011 ± 0.48
 12 h 30.128 ± 3.14 17.124 ± 2.03 15.198 ± 1.99
 24 h 13.433 ± 1.58 7.013 ± 0.99 5.294 ± 0.94
 48 h 7.125 ± 1.22 2.884 ± 0.28 2.997 ± 0.35