Table III.
Formulation | Skin microconstituent extracted (%) | ||
---|---|---|---|
Cholesterol | Triglyceride | Sphingosine | |
Skin type: excised | |||
AR (0.5%) | 18.198 ± 2.01 | 6.59 ± 0.59 | 5.863 ± 0.851 |
AR (1%) | 22.05 ± 2.65 | 16.54 ± 2.06 | 13.578 ± 1.87 |
AR (2.5%) | 38.58 ± 3.94 | 21.681 ± 3.99 | 19.962 ± 2.06 |
AR (5%) | 43.585 ± 4.68 | 36.6 ± 4.28 | 25.731 ± 2.64 |
AR (10%) | 57.732 ± 6.13 | 38.35 ± 3.64 | 29.457 ± 3.58 |
CTN (1%) | 19.120 ± 2.17 | 6.019 ± 0.58 | 7.346 ± 0.58 |
CTN (1%) + AR (1%) | 69.251 ± 4.35 | 49.11 ± 2.16 | 35.99 ± 1.97 |
Skin type: viable | |||
CTN (1% w/v) | |||
4 h | 1.711 ± 0.98 | 1.91 ± 0.25 | 0.6872 ± 0.27 |
12 h | 7.105 ± 1.108 | 12.001 ± 2.01 | 2.4023 ± 0.077 |
24 h | 2.526 ± 0.99 | 0.501 ± 0.11 | 0.28685 ± 0.061 |
48 h | 2.011 ± 0.839 | 0.489 ± 0.884 | 0.2015 ± 0.624 |
AR (1% w/v) | |||
4 h | 10.831 ± 0.91 | 8.993 ± 0.73 | 6.5016 ± 0.21 |
12 h | 21.33 ± 2.34 | 14.974 ± 1.68 | 11.25 ± 1.32 |
24 h | 12.33 ± 1.432 | 5.392 ± 0.66 | 5.61 ± 0.68 |
48 h | 6.665 ± 1.24 | 2.186 ± 0.69 | 1.008 ± 0.57 |
AR (1%) + CTN (1%) | |||
4 h | 14.263 ± 0.69 | 12.314 ± 0.68 | 8.011 ± 0.48 |
12 h | 30.128 ± 3.14 | 17.124 ± 2.03 | 15.198 ± 1.99 |
24 h | 13.433 ± 1.58 | 7.013 ± 0.99 | 5.294 ± 0.94 |
48 h | 7.125 ± 1.22 | 2.884 ± 0.28 | 2.997 ± 0.35 |