Table 3.
Relationship between components of the metabolic syndrome as well as related biological variables with the extent of coronary collateral circulation
| Collateral flow grade | 0 (n = 23) | 1 (n = 45) | 2 (n = 102) | 3 (n = 140) | 4 (n = 77) | P-value |
|---|---|---|---|---|---|---|
| Metabolic syndrome | ||||||
| No | 8 (35) | 18 (42) | 57 (56) | 77 (55) | 46 (60) | 0.005 |
| Yes | 15 (65) | 27 (58) | 45 (44) | 63 (45) | 31 (40) | |
| Number of components of MS | ||||||
| 0–1 | 2 (9) | 10 (22) | 23 (23) | 34 (24) | 23 (30) | |
| 2–3 | 10 (43) | 21 (47) | 56 (55) | 84 (60) | 40 (52) | 0.002 |
| 4–5 | 11 (48) | 14 (31) | 23 (22) | 22 (16) | 14 (18) | |
| Components of the metabolic syndrome | ||||||
| Obesity (BMI > 30 kg/m2) | 12 (52) | 18 (42) | 23 (23) | 39 (28) | 23 (30) | 0.06 |
| High blood pressure | 17 (74) | 24 (53) | 62 (61) | 68 (48) | 39 (50) | 0.04 |
| Low HDL cholesterol | 19 (83) | 32 (71) | 75 (73) | 111 (79) | 54 (70) | 0.41 |
| High triglycerides | 6 (27) | 45 (49) | 41 (40) | 57 (41) | 26 (34) | 0.33 |
| Fasting glycaemia >6.1 mmol/L | 18 (78) | 24 (56) | 49 (48) | 55 (39) | 33 (43) | 0.002 |
| Other biological variables | ||||||
| Insulin (mUI/L) | 9.60 (6.80–16.10) | 8.90 (6.90–12.60) | 6.70 (4.80–10.70) | 6.60 (4.50–11.70 | 6.50 (4.50–10.00 | 0.04 |
| HOMA-IR | 3.15 (1.97–4.41) | 2.53 (1.78–4.74) | 1.93 (1.01–3.14) | 1.61 (1.10–3.10) | 1.70 (1.08–2.71) | 0.03 |
| HbA1C (%) | 6.1 (5.4–6.6) | 5.8 (5.3–7.1) | 5.8 (5.3–7.2) | 5.6 (5.3–6.5) | 5.8 (5.3–6.6) | 0.37 |
| C-reactive protein (mg/L) | 6.99 (1.00–11.90) | 6.75 (1.88–13.12) | 6.23 (2.31–16.62) | 3.44 (1.71–8.20) | 3.44 (2.10–14.65) | 0.16 |
| Fibrinogen (g/L) | 3.96 (2.69–4.51) | 4.09 (3.30–5.20) | 4.22 (3.36–4.81) | 3.81 (3.14–4.74) | 4.03 (3.37–4.77) | 0.45 |
| Adiponectin (ng/mL) | 5170 (2462–8057) | 5480 (3385–8358) | 6648 (3421–10834) | 6807 (3674–11533) | 7529 (3664–12269) | 0.001 |
| PAI-1 (ng/mL) | 33 (19–44) | 27 (18–40) | 23 (17–35) | 22 (16–34) | 21 (16–33) | 0.01 |
MS, metabolic syndrome; BMI, body mass index. Trends were tested using Spearman’s correlations and Mantel–Haenszel linear tendency tests.