Axial, oblique and coronal micro-CT images of the same C57BL/6 mouse scanned in vivo with 88 μm voxel size without (A,D,G) and with (B,E,H) cardio-respiratory gating using a a liposomal blood pool contrast agent. The images (C,F,I) were acquired ex-vivo. The arrows indicate how the heart wall and the papillary muscles are affected by motion when no gating was used (A,D), while becoming sharp with gating (B,E). The oval region of interest (ROI) shows how the diaphragm is blurred due to respiration motion (G) in comparison with the gated acquisition (H) or the ex-vivo scanning (I). Similarly, the circle ROIs focus on the lung parenchyma and display the clear advantage of gating (E) versus not gating the acquisition (D).