Figure 1. Maternal LG has a lifelong effect on dendritic complexity and total spine density in the cortex.
(A) Representative examples of reconstructed cortical layer 2/3 pyramidal neurons in the somatosensory cortex of male adult high and low LG rats. (B,C) Dendritic complexity index calculated for the apical (B) and basal (C) dendrites of layer 2/3 pyramidal neurons of high and low LG rats. (D) Representative images of Golgi-impregnated segments from apical and basal dendrites of layer 2/3 pyramidal neurons in the somatosensory cortex of male adult high and low LG rats. (E,F) Average total spine distribution per 20 µm on the apical (E) and basal (F) dendrites in high and low LG rats. (G,H) Average spine distribution per 20 µm for each spine subtype on the apical (G) and basal (H) dendrites of high and low LG rats. Data are expressed as the mean±SEM. Asterisks indicate significant differences (* p<0.05, ** p<0.01).
