Table 1.
Rat biochemical and metabolic parameters: AGE injectiona
| Parameter | Control | AGE-RSA | AGE-RSA+ALA | RSA |
|---|---|---|---|---|
| Plasma glucose (mmol/L) | 7.4 ± 0.2 | 7.4 ± 0.2 | 7.6 ± 0.2 | 7.9 ± 0.3 |
| GHb (%) | 4.1 ± 0.2 | 3.9 ± 0.2 | 3.6 ± 0.2 | 4.1 ± 0.5 |
| Kidney wt:body wt (×10−3) | 5.1 ± 0.1 | 5.4 ± 0.1 | 5.5 ± 0.1 | 5.4 ± 0.1 |
| GFR (ml/min) | 4.3 ± 0.1 | 4.4 ± 0.2 | 4.1 ± 0.2 | 4.3 ± 0.3 |
| Systolic BP (mmHg) | 114 ± 2 | 118 ± 2 | 123 ± 3b | 121 ± 2 |
| AER (mg/24 h) | 1.2 ± 0.8 | 1.2 ± 0.2 | 1.3 ± 0.2 | 1.2 ± 0.1 |
a
Data are means ± SEM; n = 6 to 10 per group. AER, albumin excretion rate; GHb, glycated hemoglobin.
b
P < 0.01 versus control.