Table 3.
End Point | Normoalbuminuria (n = 7877) | Micro- or Macroalbuminuria (n = 3263) | HR (95% CI) |
---|---|---|---|
End-stage kidney diseaseb | 19 (0.2%) | 27 (0.8%) | 1.99 (1.08 to 3.70) |
Macrovascular eventsc | 585 (7.4%) | 415 (12.7%) | 1.61 (1.42 to 1.84) |
Cardiovascular death | 239 (3.0%) | 229 (7.0%) | 2.07 (1.72 to 2.50) |
All-cause death | 496 (6.3%) | 383 (11.7%) | 1.70 (1.48 to 1.96) |
Adjusted for age, gender, HbA1c, SBP, DBP, LDL cholesterol, HDL cholesterol, triglycerides, BMI, eGFR, current smoking, and current alcohol use.
Defined as requirement of renal replacement therapy or renal death.
Composite of nonfatal myocardial infarction, nonfatal stroke, or cardiovascular death.