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. 2009 Apr 1;20(7):1960–1969. doi: 10.1091/mbc.E08-09-0916

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Figure 6. — dup/cdt1 dominantly enhances the DNA damage phenotype in dap^−/− ovarian cysts. Wild-type (A), dap^−/− mutant (B), and dap⁻, dup^a1/dap⁻, + mutant germaria (C and D) stained with α-γ-H2Av (A–C; D, red) and C(3)G (D′, green) antibodies. The magnified images in the middle (d₁ and d₂) show C(3)G protein (green) and γ-H2Av foci (red) in one cell of a 16-cell cyst in early region 2a before the appearance of α-C(3)G staining (d₁) and in one of the two pro-oocytes in region 2a after the appearance of α-C(3)G staining (d₂). Note that γ-H2Av foci are increased in dap⁻, dup^a1/dap⁻, + cysts (C and D) compared with wild-type (A) and dap^−/− (B) cysts.