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. Author manuscript; available in PMC: 2009 Apr 1.
Published in final edited form as: Circ Res. 2008 May 29;103(1):80–88. doi: 10.1161/CIRCRESAHA.108.176057

Figure 3.

Figure 3

Production of prostanoids in EPCs and CAECs. Cells were cultured in EBM-2 (A-D) in the presence or absence of 0.5 ng/ml TNF-α for 24 h. CMs were collected and assayed for 6-keto PGF1α (A), TXB2 (B), and PGE2 (C). n=3, * P< 0.05. D: Ratio of 6-keto PGF1α/TXB2 under basal EBM-2 and TNF-α conditions. * P< 0.05. n=3. E: EPCs were incubated with EBM-2 (control), or EBM-2 + 0.1 μmol/L SC-560 for 24 h. CMs were collected for measuring of 6-keto PGF1α. Data are present as percentage of control. * P< 0.05. n=5. F: EPCs were transfected with COX-1-siRNA or Ct-siRNA for 48 h. Cells were then incubated with EGM-2 (2 ml/60 mm dish) for 2 h. The supernatants were collected for measurement of 6-keto PGF1α, n=5 *P<0.05. In all panels, open columns present EPCs and hatched columns, CAECs.

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