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. Author manuscript; available in PMC: 2009 Apr 1.
Published in final edited form as: Circ Res. 2008 May 29;103(1):80–88. doi: 10.1161/CIRCRESAHA.108.176057

Figure 8.

Figure 8

In vivo capillary formation. EPCs were treated with 30 nmol/L Ct-siRNA (A, B), PGIS-siRNA (C), or COX-1-siRNA (D) for 48 h, and then transplanted with Matrigel into nude mice. The gel plugs were excised 2 weeks after transplantation. A, control staining for mouse IgG. B-D, immunostaining for human VEGFR-2 (40X magnification). The arrow heads indicate capillaries, whereas the capillaries containing red blood cells are indicated by arrows. E, quantification of capillary formation (data presented as % of Ct-siRNA), n=4–7, *P<0.05, compared with Ct-siRNA. F: EPCs were transfected with Ct-siRNA or PPARδ-siRNA (n=4, 2 pairs at a concentration of 100 nmol/L, 2 pairs at 30 nmol/L) for 48 h, and transplanted into the nude mice (n=4, *P<0.05, compared to Ct-siRNA).

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