Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Dose effects of methylphenidate pretreatment on nicotine self-administration using two different unit doses (left panel; n=7 per group) and on sucrose-maintained responding (right panel; n=8). Data points represent the mean (±SEM) number of reinforcers earned per session as a function of methylphenidate pretreatment dose. Asterisks indicate a significant difference from the effect of saline (Sal) on self-administration of the corresponding nicotine unit dose (*p<.05, **p<.01).
