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. Author manuscript; available in PMC: 2009 Apr 1.
Published in final edited form as: Circ Res. 2008 May 29;102(12):e120–e131. doi: 10.1161/CIRCRESAHA.107.167486

Figure 1.

Figure 1

Activation of PMNs with fMLP increases caveolae-mediated transendothelial 125I-albumin permeability in RLMVEC monolayers. A, Effect of PMNs in the absence and presence of fMLP on transendothelial 125I-albumin permeability. B, Activation of PMNs with fMLP increased transendothelial 125I-albumin permeability in a PMN number-dependent manner. C, Effect of pretreatment of RLMVECs with MβCD on 125I-albumin permeability. The baseline permeability value for control group (without PMNs and fMLP) is 9.4±1.1 cm/sec. D, Effect of activation of PMNs (107 cells/mL) with fMLP (1.0 μmol/L) or PMA (0.1 μmol/L) on TER. Results are typical of 3 experiments (A through C). n=4 to 6 for each group. *P<0.05 compared with control group (without PMNs and fMLP), †P<0.05 compared with respective groups.