Table 1.

Pentoxifylline (PTX) and hydrochloric acid (HCl) effects on the arterial blood levels of Pa_O2 and Pa_CO2 at 20, 30, 90 and 180 minute time points. Data are shown as mean±SD.

	PaO2 (mmHg)				PaCO2 (mmHg)
	20 min	30 min	90 min	180 min	20 min	30 min	90 min	180 min
C-MV	124±3.6	288±11.1a	356±7.2b	397±8.3c	38±3.1	36±1.5a	36±1.3b	37±2.3c
HCl	127±1.8	62±6.1	177±6.6	127±4.7	36±3	54±2.5	55±2.6	61±4
HCl+PTX	118±6.7	67±3.4	114±7.5	254±14.6	39±2.4	54±1.5	49±0.8	53±2.9
PTX+HCl	121±7.1	121±5.3*	287±7#	377±12.4¥	36±0.8	50±2.0*	45±3.8§	46±5.1¥

No differences were observed at the 20 minute time point in the Pa_O2 and Pa_CO2 levels among all groups.

^*p<0.05 compared with HCl and HCl+PTX groups in the Pa_O2 and Pa_CO2 measurements (30 min);

^#p<0.05 compared with HCl and HCl+PTX groups in the Pa_O2 measurements (90 min);

^§p<0.05 compared with HCl group in the PaC_O2 measurement (90 min);

^¥p<0.05 compared with HCl and HCl+PTX groups in the Pa_O2 and Pa_CO2 measurements (180 min);

^ap<0.05 compared with all other groups in the Pa_O2 and Pa_CO2 measurements (30 min);

^bp<0.05 compared with all other groups in the Pa_O2 and Pa_CO2 measurements (90 min);

^cp<0.05 compared with all other groups in the Pa_O2 and Pa_CO2 measurements (180 min).