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. Author manuscript; available in PMC: 2009 Jun 1.
Published in final edited form as: Drug Discov Today Dis Mech. 2008 Jun 1;5(2):145–152. doi: 10.1016/j.ddmec.2008.04.009

Table 1.

The Five Elements of Innate Immune Defense

1) Physical barrier to microbial entry and physical danger
2) Constitutive chemical shield to inhibit microbial growth and invasion
3) Recognition system to identify the entry of foreign microbes
4) Inducible antimicrobial response triggered by the recognition system
5) Cellular recruitment process to amplify and enhance defense