Table 4.

Hazard ratios (95% confidence interval) for mortality/MI among 75,718 women without prior coronary heart disease, stroke, or cancer followed from 1996 to 2004, from multivariable models that included depression score less than 53 and use of antidepressant medication (in 1996 or 2000).^*

	Depression Score < 53		Antidepressant Medication Use
Outcome	Hazard Ratio (95% CI)	P value	Hazard Ratio (95% CI)	P value
Sudden Cardiac Death (n=99)
Age-adjusted	1.36 (0.67–2.77)	0.40	3.59 (2.20–5.86)	<0.001
Multivariable I	1.09 (0.53–2.24)	0.81	3.53 (2.15–5.81)	<0.001
Multivariable II	1.04 (0.51–2.12)	0.92	3.34 (2.03–5.50)	<0.001
Fatal CHD (n=342)
Age-adjusted	2.07 (1.43–2.99)	<0.001	1.30 (0.91–1.84)	0.15
Multivariable I	1.58 (1.09–2.29)	0.02	1.19 (0.83–1.70)	0.34
Multivariable II	1.41 (0.97–2.04)	0.07	1.07 (0.75–1.53)	0.71
Myocardial infarction (n=814)
Age-adjusted	1.14 (0.85–1.54)	0.38	1.38 (1.10–1.74)	0.006
Multivariable I	1.05 (0.78–1.41)	0.77	1.27 (1.01–1.60)	0.04
Multivariable II	0.98 (0.73–1.33)	0.91	1.21 (0.96–1.53)	0.10

CHD=coronary heart disease

^*Please see methods for description of variables for Multivariable models I and II.