. Author manuscript; available in PMC: 2009 Sep 1.

Published in final edited form as: Neurotoxicol Teratol. 2008 Mar 21;30(5):448–454. doi: 10.1016/j.ntt.2008.03.063

Table 1.

Weight of pregnant guinea pigs treated once daily with vehicle (saline, 1 ml/kg), methadone (12 mg/kg), or morphine (15 mg/kg) starting at day 35 of gestation

	Vehicle	Methadone	Morphine
Maternal wt. at parturition (g)	1040 ± 39	869 ± 21^***	913 ± 28^**
Wt. gain (% of treatment start wt)	50 ± 6	30 ± 2^**	34 ± 2^*
N (dams/treatment)	9	11	10

p<0.05 vs. vehicle

^**

p<0.01 vs. vehicle

^***

p<0.001 vs. vehicle; all values reported as mean ± S.E.