Table 2.
Weights (g) of in utero opioid exposed neonatal guinea pigs compared to vehicle
Age | Vehicle | Methadone | Morphine |
---|---|---|---|
Birth | 102 ± 4 | 81 ± 4** | 82 ± 3** |
3 days | 102 ± 4 | 82 ± 5** | 84 ± 3** |
7 days | 132 ± 6 | 116 ± 8* | 112 ± 5** |
14 days | 189 ± 12 | 147 ± 10*^^ | 178 ± 9 |
p<0.05 vs. vehicle
p<0.01 vs. vehicle
p<0.001 vs. vehicle
p<0.01 vs. morphine, all values reported as mean ± S.E. of all pups in each treatment group, n (per treatment): Birth and day 3, 18 pups; day 7, 12 pups; day 14, 6 pups.