Table 1.

Distribution of GLV-1h68 virus in female and/or male nude mice with s.c. PANC-1 tumors 2 wk (A), 1 mo (B), and 85 d (C) after i.v. viral injection

(A) 2 wk
	Viral titer in tissue samples (pfu/organ or tumor)
	Female				Male
Animal no.	1	2	3	4	5	6	7	8
Kidneys	0	0	79	0	0	0	0	0
Spleen	37	447	584	331	68	229	212	274
Ovaries/testes	0	1.6 × 104	1.5 × 104	0	0	0	0	0
Liver	0	820	0	0	0	0	0	0
Lungs	0	222	67	224	38	630	203	427
Brain	0	0	0	0	0	0	0	0
Tumor	5.7 × 107	3.9 × 108	1.7 × 108	3.2 × 108	5.1 × 107	4.3 × 107	6.4 × 107	3.3 × 107

(B) 1 mo
	Viral titer in tissue samples (pfu/organ or tumor)
	Female			Male
Animal no.	1	2	3	4	5	6
Kidneys	0	0	0	0	0	0
Spleen	0	527	339	0	0	88
Ovaries/testes	0	0	0	0	0	0
Liver	0	0	0	0	0	0
Lungs	178	185	493	0	0	710
Brain	0	0	0	0	0	0
Tumor	3.8 × 108	8.8 × 108	5.3 × 108	6.0 × 108	3.3 × 108	9.9 × 108

(C) 85 d
	Viral titer in tissue samples (pfu/organ or tumor)
	Male
Animal no.	1	2	3	4	5
Kidneys	0	0	0	5	0
Spleen	0	0	0	2	0
Bladder	0	0	0	5	0
Testes	7	0	0	9	0
Liver	0	0	0	0	0
Heart	0	0	0	50	0
Lungs	4	0	0	311	0
Brain	0	0	0	1	15
Tumor	9.6 × 104	7.4 × 105	3.6 × 107	1.5 × 105	5.3 × 103