Fig. 3.
Effect of autophagy gene inhibition on survival of adult flies. (A–E) Survival of control and autophagy-inhibited flies. Survival is plotted as a function of adult age in days. Each curve represents >125 flies, cultured as adults at 29°C. Solid lines indicate minus-drug, dashed lines indicate plus-drug. Mean life span was calculated for plus-drug (+) and minus-drug (−) cohorts, with SD in parentheses, followed by the percent change. Median is presented for each cohort, followed by percent change and p value generated using log-rank tests. (A) Oregon-R controls. (B) w[1118] controls. (C) Atg5 RNAi. (D) Atg7 RNAi. (E) Atg12 RNAi.