Table 1.
Clofazimine | ||||||||
%–ΔcGI | ||||||||
Clofazimine | MAP | M. avium | M. bovis | |||||
μg/ml | Human | Bovine | Bovine | BCG | ||||
Dominic | UCF-4 | Ben | 19698 | 303 | 25291 | 101 | 19015 | |
1 | -99% | -99% | -99% | -99% | -99% | -98% | -98% | -99% |
4 | -99% | -99% | -99% | -99% | -99% | -98% | -98% | -98% |
16 | -99% | -99% | -99% | -99% | -99% | -98% | -98% | -98% |
64 | -99% | -99% | -99% | -99% | -99% | -99% | -99% | -99% |
Data are presented for a single agent, Clofazimine, the positive antibiotic control. Data are given for a representative experiment of each mycobacterial strain studied. Note maximal inhibition at 1 μg/ml. for every strain. %–ΔcGI = Percent decrease in cumulative Growth Index compared to solvent control (see Methods.)