Table I.
Clinicopathologic parameters and the expression status of NDRG2
| Characterstics | Total | NDRG2 expression level |
P | |||
| Negative/low |
High |
|||||
| n | % | n | % | |||
| Age (years) | 0.0561 | |||||
| <50 | 37 | 27 | 73.0 | 10 | 27.0 | |
| ≥50 | 62 | 28 | 45.2 | 34 | 54.8 | |
| Gender | 0.1795 | |||||
| Female | 51 | 25 | 49.0 | 26 | 51.0 | |
| Male | 48 | 30 | 62.5 | 18 | 37.5 | |
| Site | 0.5187 | |||||
| Right/transverse colon | 28 | 17 | 60.7 | 11 | 39.3 | |
| Left colon and rectum | 71 | 38 | 53.5 | 33 | 46.5 | |
| Size | 0.4251 | |||||
| <5 cm in diameter | 60 | 32 | 53.3 | 28 | 46.7 | |
| ≥5 cm in diameter | 39 | 23 | 59.0 | 16 | 41.0 | |
| Differentiation | <0.0001 | |||||
| Well | 28 | 5 | 17.9 | 23 | 82.1 | |
| Moderately | 46 | 25 | 54.3 | 21 | 45.7 | |
| Poorly | 25 | 25 | 100 | 0 | 0 | |
| Invasion depth | 0.0015 | |||||
| T1 | 3 | 0 | 0 | 3 | 100 | |
| T2 | 18 | 4 | 22.2 | 14 | 77.8 | |
| T3 | 72 | 48 | 66.7 | 24 | 33.3 | |
| T4 | 6 | 3 | 50.0 | 3 | 50.0 | |
| Nodal status | 0.0719 | |||||
| N0 | 44 | 20 | 45.5 | 24 | 54.5 | |
| N1 | 55 | 35 | 63.6 | 20 | 36.4 | |
| Distant metastasis | 1.00 | |||||
| M0 | 90 | 50 | 55.6 | 40 | 44.4 | |
| M1 | 9 | 5 | 55.6 | 4 | 44.4 | |
| Dukes’ stage | 0.0004 | |||||
| A | 17 | 2 | 11.8 | 15 | 88.2 | |
| B | 27 | 18 | 66.7 | 9 | 33.3 | |
| C | 55 | 35 | 63.6 | 20 | 36.4 | |