Table 5. Percentage of CD4+ and CD8+ T cells with effector/memory and central/memory phenotype in 18 TB patients at treatment completion.
| Patients | P value | ||
| Group A (n = 8) | Group B (n = 10) | ||
| CD4+ T cells | |||
| TEM% (range) | 21,27 (2,61–27,1) | 41,7 (12,36–52,65) | 0,001 |
| TCM% (range) | 2,36 (1,69–15,9) | 15,82 (11,25–28,39) | 0,003 |
| CD8+ T cells | |||
| TEM% (range) | 11,2 (5,6–21,4) | 18,55 (12,5–35,6) | 0,036 |
| TCM% (range) | 9,9 (3,1–14) | 14 (6,7–22) | 0,087 |
Abbreviations:
TEM: T cells with an effector/memory phenotype, defined as CD45RO+/CCR7−.
TCM: T cells with central/memory phenotype, defined as CD45RO+/CCR7+.
Group A: TB patients who had a QFT-G reversion (positive to negative) at the end of therapy.
Group B: TB patients who remained QFT-G positive at the end of therapy.