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. 2009 Apr 13;4(4):e5179. doi: 10.1371/journal.pone.0005179

Table 6. Sensitivities and average scores of the different HMMs for evolutionarily distant retroviral LTRs at high specificity.

Thre-shold Beta exo-genous HML cons Beta opossum Alpha-beta chicken Alpha exo-genous Lenti Delta Spuma Epsilon Gamma exo-genous HERV-gamma cons Gamma opossum
Size of test set 3 23 89 47 3 8 8 7 4 3 69 474
Average length of LTRs 382 728 332 290 325 412 700 1177 809 554 630 448
Hml 5 −14 40* −43 −49 −31 −11 −16 −15 −33 −20 −13 −34
0 100% 1.1% 0 0 0 0 0 0 0 0 0
Gamma 5 −14 1.9 −13 −17 −23 −0.41 −0.14 −6.6 −8.2 12* 23* −9.9
0 22% 3.4% 0 0 2/8 1/8 0 0 3/3 97% 9.1%
Beta 7 2.3 18* −5.8 1.5* 16* 3.7** 8.6* 1.8 −11 −8.1 2.1 −6.4
1/3 100% 9.0% 32% 3/3 1/8 4/8 1/7 0 0 12% 1.9%
Lenti 3 −15 −5.2 −18 −17 −11 34* −7.1 −14 −18 −7.8 −6.5 −16
0 8.7% 0 0 0 100% 0 0 0 0 4.3% 3.0%
General 4 −2.2 9.4* −5.9 −1.9* 5.0* 5.6** 3.0* −1.1 −8.5 −3.6* 7.5* −4.8
1/3 96% 15% 30% 2/3 5/8 4/8 0 0 0 86% 10%

The thresholds were the same as in the RepeatMasker comparison in Table 2. (*) indicates that at least some LTRs in the LTR set are in the training set of the HMM model. (**) indicates that the set was used in the test set. The “beta”, “alphabeta”, “delta”, “spuma” and “gamma” categories contained ERVs and/or XRVs, further described in [1].