Figure 6. Experimentally measured and predicted values for the 156-residue ribonuclease HI protein.

The plots at left show the predictions made by the CUPSAT physicochemical modeling program, the consensus approach, and the PIPS phylogenetic inference program using the informative, regularizing, and hydrophobicity priors. To the right is the phylogenetic tree of 239 sequences that was utilized by the PIPS program. The values are the squared Pearson correlation coefficients.