Fig. 4.

Axotomy induces supernumerary peripheral axons differing in size and trajectory. a: Putative D-hair follicle afferent axon in the nerve proximal to the site of axotomy. Open arrows point distally. Solid arrows indicate branch points where fine unmyelinated axons originate. Arrowheads point to hairpin loops. b: Axons from same afferent distal to the site of injury. c: Camera lucida drawing showing the course and branching pattern of a putative guard hair follicle afferent within a terminal neuroma (outline of neuroma indicated by large solid line). Both afferents were axotomized 7 weeks earlier. Scale bars = 10 μm in b (applies to a,b); 100 μm in c.