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ISO increases [Ca2+]i in EPI cells to a larger extent than in ENDO cells. (A) Action potential-evoked [Ca2+]i transients from representative ENDO and EPI cells before and after the application of 100 nM ISO. (B) Bar plot of the mean±SEM of the amplitude of [Ca2+]i transients of ENDO and EPI cells under control conditions and in the presence of ISO. *=p<0.05.
