Table 3.

Collagen Content in Left Ventricular Regions at 28 Days After Myocardial Infarction: Effects of Saline or Fibrin-Alginate Injection at 7 Days After Myocardial Infarction

	Saline	Fibrin- Alginate	Within Group (Region)	Between Group	Interaction
Fibrillar collagen content (morphometry, %)
Remote	8.3 ± 1.0	8.6 ± 1.1	<0.001	<0.001	0.017
Border	17.4 ± 1.6^a	25.0 ± 3.6^a ^b
MI	64.2 ± 2.6^a ^c	56.5 ± 4.0^a ^b ^c
Hydroxyproline (µg/mg of dry tissue, weight)
Remote	3.5 ± 0.4	3.3 ± 0.3	<0.001	0.485	0.915
Border	5.9 ± 1.5	5.1 ± 0.7
MI	12.8 ± 1.7^a ^c	11.6 ± 1.5^a ^c
Soluble collagen (µg/mL)
Remote	48.4 ± 2.9	45.4 ± 2.7	<0.001	0.020	0.237
Border	52.2 ± 2.8	53.5 ± 4.0
MI	71.0 ± 6.1^a ^c	59.1 ± 3.5^a ^b
Sample size (n)	9	8

p < 0.05 vs remote.

p < 0.05 vs saline.

p< 0.05 vs border.

Values presented as mean ± standard error of the mean.

MI = myocardial infarction.