Table 6.
Prevalence of CKD Stages 1–4: Sex-Specific Albumin-Creatinine Ratio Cut Points: MDRD Study vs. Mayo vs. Cockcroft-Gault Estimating Equations
| Estimating Equation |
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| MDRD Study |
Mayo |
Cockcroft-Gault |
|||||||||
| CKD Stage |
Prevalence %* |
95% CI | Population n† |
Prevalence %* |
95% CI | Population n† |
Prevalence Ratio‡ |
Prevalence %* |
95% CI | Population n† |
Prevalence Ratio§ |
| 1 | 3.09 | 2.82–3.37 | 6,705,123 | 3.82 | 3.48–4.18 | 8,301,600 | 1.23 | 2.77 | 2.52–3.04 | 6,019,747 | 0.90 |
| 2 | 4.55 | 4.18–4.94 | 9,883,203 | 3.81 | 3.41–4.24 | 8,279,868 | 0.84 | 3.62 | 3.29–3.99 | 7,866,961 | 0.79 |
| 3 | 7.98 | 7.31–8.71 | 17,344,870 | 5.78 | 5.31–6.29 | 12,561,060 | 0.72 | 17.31 | 16.45–18.21 | 37,617,984 | 2.17 |
| 4 | 0.35 | 0.27–0.47 | 768,757 | 0.52 | 0.41–0.67 | 1,130,061 | 1.47 | 1.15 | 0.97–1.38 | 2,499,173 | 3.23 |
| 1–4 | 15.97 | 15.16–16.81 | 34,701,953 | 13.93 | 13.23–14.65 | 30,272,589 | 0.87 | 24.86 | 23.82–25.93 | 54,025,597 | 1.56 |
| 3–4 | 8.34 | 7.66–9.07 | 18,113,627 | 6.30 | 5.80–6.85 | 13,691,121 | 0.76 | 18.47 | 17.52–19.45 | 40,138,889 | 2.22 |
Abbreviations: CI, confidence interval; CKD, chronic kidney disease; MDRD, Modification of Diet in Renal Disease.
Prevalence estimates of stages 1 and 2 incorporate persistence estimates for microalbuminuria of 53.9% if estimated glomerular filtration rate ≥ 90 mL/min/1.73 m2 (≥ 1.50 mL/s/1.73 m2) and 72.7% if 60–89 mL/min/1.73 m2 (1.00–1.48 mL/s/1.73 m2).
Population n based on the estimated 2006 US population aged 20 years and older: 217,319,378.
Mayo:MDRD
Cockcroft-Gault:MDRD